Before we dive into this fiery, tangy, utterly addictive Spicy Southern Comeback Sauce, let me just say—thank you for being here. Whether you’re a long-time reader or someone who just stumbled across this corner of the internet, I’m so grateful you’re stopping by. This sauce is one of those Southern staples that deserves to be shared, savored, and, honestly, slathered on everything!
Spicy Southern Comeback Sauce is more than just a condiment—it’s a flavor-packed hug from the South with a punch of heat and personality. Right after I first whipped up a batch of this, I knew I had to bring it to you. It’s quick, easy, and so versatile. And yes, it totally lives up to the name—you’ll keep coming back for more!
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What Is Southern Comeback Sauce?
Comeback Sauce originated in Mississippi and is a beloved Southern classic, often found on everything from fried chicken sandwiches to french fries. Think of it as a zesty, slightly spicy cousin of remoulade or a bolder version of Thousand Island dressing. It’s creamy, tangy, smoky, and just a little bit sweet—with a kick that keeps you reaching for more.
Why You’ll Fall in Love With This Spicy Southern Comeback Sauce
There’s so much to adore here:
- Ridiculously easy: Just mix and chill.
- Customizable: Like it hotter? Add more cayenne. Sweeter? Drizzle in a bit of honey.
- Multi-purpose: Use it as a dip, spread, or salad dressing.
- Flavor bomb: It brings smoky heat, tangy zing, and creamy comfort in every bite.
What Does It Taste Like?
This sauce is rich and creamy from the mayo, with a tangy zip from vinegar and ketchup, plus layers of flavor from Dijon mustard, Worcestershire sauce, and spices. The smoked paprika and cayenne bring warmth and just enough heat to wake up your taste buds—anything but boring!!
The Perks of Making It at Home
- Fresh and customizable: You’re in control of the spice and sweetness.
- Budget-friendly: Uses pantry staples you likely already have.
- No preservatives: Unlike store-bought sauces.
- Impress-your-guests level good: They’ll be asking for the recipe, guaranteed!

Ingredients for Spicy Southern Comeback Sauce
Here’s what you’ll need:
- 1/2 cup mayonnaise
- 1/4 cup ketchup
- 2 tablespoons Dijon mustard
- 1 tablespoon hot sauce (Tabasco or your favorite brand)
- 1 tablespoon Worcestershire sauce
- 1 tablespoon apple cider vinegar
- 1 teaspoon garlic powder
- 1 teaspoon onion powder
- 1/2 teaspoon smoked paprika
- 1/2 teaspoon cayenne pepper (adjust to taste)
- Salt and pepper, to taste
Ingredient Substitutions & Additions
- Mayonnaise: Greek yogurt works for a lighter version.
- Hot Sauce: Sriracha adds a slightly sweeter, garlicky kick.
- Sweeten It Up: A teaspoon of honey balances the heat beautifully.
- Make It Vegan: Use vegan mayo and check labels for vegan-friendly sauces.
Tools You’ll Need
- A medium mixing bowl
- A whisk or spoon
- Measuring cups and spoons
- An airtight container for storage
How to Make Spicy Southern Comeback Sauce
Prep time: 5 minutes | Chill time: 30 minutes | Total time: 35 minutes
Step-by-Step Instructions
- Mix the base: In a medium bowl, combine mayonnaise, ketchup, Dijon mustard, hot sauce, Worcestershire sauce, and apple cider vinegar.
- Add spices: Stir in garlic powder, onion powder, smoked paprika, cayenne pepper, salt, and pepper.
- Whisk it up: Whisk until everything is silky smooth and well blended.
- Taste test: Adjust seasoning as needed—more heat, more tang, more sweet, make it yours!
- Chill out: Refrigerate the sauce for at least 30 minutes to let the flavors come together.
What to Serve With Spicy Southern Comeback Sauce
This sauce plays so well with:
- Crispy fried chicken or tenders
- Grilled shrimp skewers
- Sweet potato fries
- Burgers and sliders
- Roasted veggies
- A Southern-style po’ boy sandwich
- Or even as a salad dressing—yes, really!
I promised you versatile, and here’s proof!
Tips for the Best Comeback Sauce Ever
- Let it chill: Don’t skip the 30-minute rest—it makes a big difference!
- Make it ahead: It actually tastes even better the next day.
- Taste as you go: Everyone’s heat tolerance is different—customize it to your liking.
- Use high-quality mayo: Since mayo is the base, a good one really elevates the flavor.
How to Store It
- Store in an airtight container in the fridge.
- Keeps for up to 1 week.
- Give it a quick stir before serving—some separation is normal.
Frequently Asked Questions
What’s the difference between Comeback Sauce and Remoulade?
Remoulade is more herb-forward and sometimes includes pickles or horseradish, whereas Comeback Sauce leans creamier and spicier with that signature Southern zing.

Is this sauce really spicy?
It has a kick, thanks to the cayenne and hot sauce, but it’s totally adjustable. If you’re sensitive to heat, start with half the cayenne and add more to taste.
Can I freeze it?
Nope, mayo-based sauces don’t freeze well—they tend to separate and get weird. Best to enjoy it fresh from the fridge!
Is it gluten-free?
Yes—just double-check your Worcestershire sauce and hot sauce labels to be sure.
Wrapping It Up: Why You’ll Keep Coming Back to This Sauce
This Spicy Southern Comeback Sauce is everything you want in a dipping sauce—creamy, spicy, tangy, and totally irresistible. It’s the kind of recipe you make once and wonder how you ever lived without it. Whether you’re hosting game day, meal prepping lunches, or just elevating your weeknight dinner, this sauce delivers flavor in spades.
Looking for more bold Southern-inspired flavors? Try these reader favorites next:
- Southern Peach BBQ Chicken
- Easy Honey Jalapeño Cornbread
- Baked Cajun Shrimp & Grits
Let’s Keep Cooking Together!
If you try this recipe, I’d love to hear how it turned out! Leave a comment below, snap a photo and tag me on Pinterest, or share your twist on the classic!
Nutritional Information (Per Serving)
- Calories: 80
- Fat: 8g
- Carbohydrates: 2g
- Protein: 0g
- Sugar: 1g
- Sodium: ~200mg
Thanks again for being here—happy cooking, and I hope this sauce makes your next meal extra special 💛
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Spicy Southern Comeback Sauce: The Bold, Creamy Dip You’ll Want on Everything
- Total Time: 0 minutes
- Yield: 35 minutes 1x
Description
Spicy Southern Comeback Sauce is creamy, bold, and bursting with zesty flavor! This Mississippi-born classic is a Southern favorite you’ll want to slather on everything—fries, chicken, burgers, shrimp, and more. It’s quick to whip up, packed with pantry staples, and gets even better after chilling. Make a batch and watch it disappear!
Ingredients
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1/2 cup mayonnaise
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1/4 cup ketchup
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2 tablespoons Dijon mustard
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1 tablespoon hot sauce (such as Tabasco or your preferred brand)
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1 tablespoon Worcestershire sauce
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1 tablespoon apple cider vinegar
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1 teaspoon garlic powder
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1 teaspoon onion powder
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1/2 teaspoon smoked paprika
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1/2 teaspoon cayenne pepper (adjust to taste)
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Salt and pepper, to taste
Instructions
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In a medium bowl, stir together mayonnaise, ketchup, Dijon mustard, hot sauce, Worcestershire sauce, and apple cider vinegar.
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Add garlic powder, onion powder, smoked paprika, cayenne pepper, salt, and pepper.
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Whisk until smooth and fully combined.
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Taste and adjust seasoning to your liking—more heat, more tang, or a bit of sweetness if desired.
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Chill for at least 30 minutes to let the flavors meld beautifully.
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Serve with fried chicken, shrimp, fries, sandwiches, or veggies!
Notes
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Make it your own: Add a teaspoon of honey for a sweet twist, or swap hot sauce brands for different heat levels.
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Let it rest: Don’t skip the chill time—it really brings the flavors together!
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Lighter option: Sub in Greek yogurt for mayo if you’re looking for a healthier version.
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Storage: Keep in an airtight container in the fridge for up to 1 week.
- Prep Time: 5 minutes
- Cook Time: 30 minutes
- Category: 8 servings
- Method: Condiment
- Cuisine: Mixing
Nutrition
- Serving Size: 2 tablespoons
- Calories: 80
- Sugar: 1g
- Sodium: 200mg
- Fat: 8g
- Saturated Fat: 1.5g
- Unsaturated Fat: 6g
- Trans Fat: 0g
- Carbohydrates: 2g
- Fiber: 0g
- Protein: 0g
- Cholesterol: 5mg
Keywords: Spicy Southern Comeback Sauce, Southern dipping sauce, spicy mayo dip, easy homemade sauce